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Cefquinome sulfate

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Products Intro: Product Name:Cefquinome
CAS:118443-89-3
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CAS:118443-89-3
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CAS:118443-89-3
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CAS:118443-89-3
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Products Intro: Product Name:Cefquinome sulfate
CAS:118443-89-3
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Cefquinome sulfate manufacturers

  • Cefquinome Sulfate
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  • 2025-11-03
  • CAS:118443-89-3
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  • 2025-11-03
  • CAS:118443-89-3
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  • 2025-10-26
  • CAS:118443-89-3
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Related articles

Cefquinome sulfate Basic information
Definition
Product Name:Cefquinome sulfate
Synonyms:CEFQUINOME SULFATE;Quinolinium, 1-(6R,7R)-7-(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetylamino-2-carboxy-8-oxo-5-thia-1-azabicyclo4.2.0oct-2-en-3-ylmethyl-5,6,7,8-tetrahydro-, sulfate (1:1);(6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate;7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-8-oxo-3-(5,6,7,8-tetrahydroquinolin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;Cefoquiuonie sulphate;[6R-[6α,7β(Z)]]-1-;1-[[(6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]Methyl]-5,6,7,8-tetrahydro-quinoliniuM Sulfate;HR 111V Sulfate
CAS:118443-89-3
MF:C23H25N6O5S2.HO4S
MW:626.69
EINECS:800-041-1
Product Categories:Pharmaceuticals;Sulfur & Selenium Compounds;cephalosporins antibiotics;API;Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals
Mol File:118443-89-3.mol
Cefquinome sulfate Structure
Cefquinome sulfate Chemical Properties
Melting point 161-166°C
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
InChIKeyKYOHRXSGUROPGY-NIZYHBPXNA-N
SMILESS(O)([O-])(=O)=O.C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3=CSC(N)=N3)=N\OC)C(=O)N12)C[N+]1=CC=CC2CCCCC1=2)(=O)O |&1:10,12,r|
Safety Information
MSDS Information
Cefquinome sulfate Usage And Synthesis
DefinitionNCIt: Cefquinome Sulfate is the sulfate form of cefquinome, a semisynthetic, broad-spectrum, fourth-generation aminothiazolyl cephalosporin with antibacterial activity. Cefquinome binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
DescriptionCefquinome sulfate is a veterinary, parenteral, fourth-generation cephalosporin belonging to the class of aminothiazolyl compounds. They have high cell permeability and high stability to beta-lactamases. They have broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria (e.g. Pseudomonas aeruginosa and Enterobacteriaceae).
Chemical PropertiesCefquinome sulfate is Off-White Solid
UsesCefquinome sulfate is an antibacterial used in veterinary medicine. Used in the treatment of infections caused by pathogens such as S. aureus, E. coli, Streptococcus, P. multocida and A. pleuropneumoniae. Also used to trea t mastitis in dairy cows.
UsesAn antibacterial used in veterinary medicine. Used in the treatment of infections caused by pathogens such as S. aureus, E. coli, Streptococcus, P. multocida and A. pleuropneumoniae. Also used to treat mastitis in dairy cows.
Mechanism of actionCefquinome sulfate acts by inhibition of the cell wall synthesis, but it has a relatively short half-life of about 2.5 hours. It is less than 5% protein bound and is excreted unchanged in the urine.
IC 50β-lactam
Cefquinome sulfate Preparation Products And Raw materials
Tag:Cefquinome sulfate(118443-89-3) Related Product Information
2,2'-Dithiobis(benzothiazole) MTT Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Benzothiazole Cefquinome Dimethyl sulfate Magnesium sulfate heptahydrate Ammonium sulfate Sodium sulfate Cefoselis sulfate Cefpirome sulfate 2-Methyl-4-isothiazolin-3-one Barium sulfate Aluminum sulfate sulfate 5,6,7,8-Tetrahydroquinoline Cefquinome sulfate

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