1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-

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1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- Basic information
Product Name:1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-
Synonyms:1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-;PST3 1a (NSC-753859);3-hydroxy-4,5-bis(benzyloxy)-6-((benzyloxy)methyl)-2-phenyl-2-oxo-2λ?-[1,2]oxaphosphinane
CAS:1096144-06-7
MF:C32H33O6P
MW:544.57
EINECS:
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Mol File:1096144-06-7.mol
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- Structure
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- Chemical Properties
Boiling point 668.2±65.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
pka11.94±0.70(Predicted)
Safety Information
MSDS Information
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- Usage And Synthesis
UsesPST3.1a is a N-acetylglucosamine glycosyltransferase (MGAT5) inhibitor with the IC50 of 2 μM. PST3.1a inhibits glioblastoma-initiating cell invasiveness and proliferation[1].
References[1] Hassani Z, et al. Phostine PST3.1a Targets MGAT5 and Inhibits Glioblastoma-Initiating Cell Invasiveness and Proliferation. Mol Cancer Res. 2017;15(10):1376-1387. DOI:10.1158/1541-7786.MCR-17-0120
1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)- Preparation Products And Raw materials
Tag:1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-(1096144-06-7) Related Product Information
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