4-Quinazolinamine, N-(1-ethylpropyl)-6,7,8-trimethoxy-, hydrochloride (1:1) manufacturers
- PF04471141 HCl
-
- $1980.00
-
2026-04-20
- CAS:1655498-17-1
- Purity:
- Supply Ability: 10g
|
| | 4-Quinazolinamine, N-(1-ethylpropyl)-6,7,8-trimethoxy-, hydrochloride (1:1) Basic information |
| | 4-Quinazolinamine, N-(1-ethylpropyl)-6,7,8-trimethoxy-, hydrochloride (1:1) Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: 20mg/mL, clear | | form | powder | | color | white to beige | | InChI | 1S/C16H23N3O3.ClH/c1-6-10(7-2)19-16-11-8-12(20-3)14(21-4)15(22-5)13(11)17-9-18-16;/h8-10H,6-7H2,1-5H3,(H,17,18,19);1H | | InChIKey | QRHFQSUUJMOIHO-UHFFFAOYSA-N | | SMILES | CCC(CC)NC1=NC=NC2=C(OC)C(OC)=C(OC)C=C21.Cl |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 4-Quinazolinamine, N-(1-ethylpropyl)-6,7,8-trimethoxy-, hydrochloride (1:1) Usage And Synthesis |
| Description | PF-04471141 is a potent, selective inhibitor of the calcium-activated phosphodiesterase PDE1. (PDE1B IC50 = 35 nM). | | Uses | PF-04471141 (hydrochloride) is a compound that regulates intracellular cAMP and cGMP concentrations. It is a PDE1 inhibitor and has different effects on different PDE enzymes in regulating intracellular signaling molecule concentrations and cell proliferation in vascular smooth muscle cells. | | References | [1] Cyclic nucleotide signalling compartmentation by PDEs in cultured vascular smooth muscle cells DOI:10.1111/bph.14651 |
| | 4-Quinazolinamine, N-(1-ethylpropyl)-6,7,8-trimethoxy-, hydrochloride (1:1) Preparation Products And Raw materials |
|