CHS-111

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CHS-111 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:CHS-111；CHS 111;CHS111
CAS:886755-63-1
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:CHS-111
CAS:886755-63-1
Package:25mg;1520USD|100mg;2500USD|50mg;1980USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:CHS-111
CAS:886755-63-1
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800

CHS-111 manufacturers

  • CHS-111
  • CHS-111 pictures
  • $1520.00
  • 2026-05-11
  • CAS:886755-63-1
  • Purity:
  • Supply Ability: 10g
CHS-111 Basic information
Product Name:CHS-111
Synonyms:CHS 111;CHS111;CHS-111
CAS:886755-63-1
MF:C21H18N2O
MW:314.39
EINECS:
Product Categories:
Mol File:886755-63-1.mol
CHS-111 Structure
CHS-111 Chemical Properties
Safety Information
MSDS Information
CHS-111 Usage And Synthesis
DescriptionCHS-111 is a benzyl indazole compound which inhibits superoxide anion (O(2)(-)) generation. CHS-111 also reduced the fMLP- but not phorbol ester-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homology (Rho) A, and reduces the membrane recruitment of RhoA in fMLP-stimulated cells.
UsesCHS-111 is a benzyl indazole inhibitor of superoxide anion O2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC50 of 3.9 μM[1].
References[1] Chang LC, et al. Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils. Biochem Pharmacol. 2011;81(2):269-278. DOI:10.1016/j.bcp.2010.10.007
CHS-111 Preparation Products And Raw materials
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