| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:2(S)-AMino-4-azido-butanoic Acid
CAS:120042-14-0
Package:50Mg,5Mg
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| | L-Azidohomoalanine Basic information |
| | L-Azidohomoalanine Chemical Properties |
| Melting point | 220-2230C | | storage temp. | -20°C Freezer | | solubility | Water | | form | Solid | | color | Off-White |
| | L-Azidohomoalanine Usage And Synthesis |
| Description | L-azidohomoalaine provides a fast, sensitive, non-toxic and non-radioactive alternative to the traditional radioactive technique, 35S-methionine for the detection of nascent protein. L-azidohomoalaine is an amino acid analog that contains a small modification and its azido moiety can be fed to cultured cells and incorporated into proteins during active protein synthesis. | | Chemical Properties | Off-White Solid | | Uses | 2(S)-Amino-4-azido-butanoic Acid is a novel mutagenic amino acid. | | Synthesis | A concise and highly efficient synthetic route to l-azidohomoalanine (l-Aha) and its homologues is presented here. Starting from inexpensive N-Boc-O-Bn-l-aspartic acid, gram quantities of l-Aha hydrochloride can be prepared with high purity. The reactions can be completed within 1 week and the products can be incorporated into proteins using l-methionine auxotrophs.
| | IC 50 | Alkyl-Chain | | References | [1] STEFANIE ROTH Neil R T William C Drewe. A concise and scalable route to L-azidohomoalanine[J]. Nature Protocols, 2010, 5 12: 1967-1973. DOI:10.1038/nprot.2010.164. |
| | L-Azidohomoalanine Preparation Products And Raw materials |
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