替诺柳
| 中文名称 | 替诺柳 |
|---|---|
| 中文同义词 | 替诺柳;化合物 T13122;化合物 TENOSAL |
| 英文名称 | Tenosal |
| 英文同义词 | Tenosal;2-(2-thiophenecarboxy)benzoic acid;2-(thiophene-2-carbonyloxy)benzoic acid;2-Thiophenecarboxylic acid, 2-carboxyphenyl ester |
| CAS号 | 95232-68-1 |
| 分子式 | C12H8O4S |
| 分子量 | 248.257 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 95232-68-1.mol |
| 结构式 |  |
替诺柳 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Tenosal 是一种通过将水杨酸与 2-噻吩羧酸酯化而得到的新型化合物，具有抗炎，镇痛和退热特性。
Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA.