Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester

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Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester Basic information
Product Name:Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester
Synonyms:Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester;Sulfane Sulfur Probe 4;3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-mercaptobenzoate);Fluorescein di(2-thiobenzoate)(SSP4)
CAS:1810731-98-6
MF:C34H20O7S2
MW:604.65
EINECS:
Product Categories:
Mol File:1810731-98-6.mol
Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester Structure
Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester Chemical Properties
Boiling point 806.4±65.0 °C(Predicted)
density 1.53±0.1 g/cm3(Predicted)
solubility Chloroform: Soluble
DMF: Soluble
DMSO: Soluble
form Solid
pka5.35±0.43(Predicted)
color White to off-white
Safety Information
MSDS Information
Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester Usage And Synthesis
UsesSulfane sulfur probe 4 (SSP4) is a fluorescent probe used to detect sulfane sulfur species (Ex/Em=494/515 nm). Sulfane sulfur probe 4 exhibits high sensitivity in detecting sulfane sulfur, even in the presence of other substances such as homocysteine, methionine, cysteine, glutathione, N-acetyl-L-cysteine, glycine, tyrosine, tryptophan, arginine, and metal ions (Fe2+, Fe3+, Mg2+, Ca2+, and Zn2+)[1].
References[1] Shieh M, et al. Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs[J]. Redox Biology, 2022, 56: 102433. DOI:10.1016/j.redox.2022.102433
[2] SOFIA-IRIS BIBLI . A selective and sensitive method for quantification of endogenous polysulfide production in biological samples[J]. Redox Biology, 2018, 18: Pages 295-304. DOI: 10.1016/j.redox.2018.07.016
[3] WIEDERSCHAIN G Ya. The Molecular Probes handbook. A guide to fluorescent probes and labeling technologies[J]. Biochemistry (Moscow), 2011, 76 11: 1276-1276. DOI: 10.1134/s0006297911110101
[4] YUKA KIMURA. Identification of H2S3 and H2S produced by 3-mercaptopyruvate sulfurtransferase in the brain.[J]. Scientific Reports, 2015: 14774. DOI: 10.1038/srep14774
[5] MITSUTAKA FUKUDOME. Reactive Sulfur Species Interact with Other Signal Molecules in Root Nodule Symbiosis in Lotus japonicus.[J]. Antioxidants, 2020. DOI: 10.3390/antiox9020145
Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester Preparation Products And Raw materials
Tag:Benzoic acid, 2-mercapto-, 6'-[(2-mercaptobenzoyl)oxy]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl ester(1810731-98-6) Related Product Information
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