Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]-

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Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- manufacturers

  • ERCC1-XPF-IN-2
  • ERCC1-XPF-IN-2 pictures
  • $34.00
  • 2026-07-15
  • CAS:1808986-37-9
  • Purity: 98.34%
  • Supply Ability: 10g
Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- Basic information
Product Name:Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]-
Synonyms:Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]-;ERCC1-XPF-IN-2;2-(2,4-Dichlorophenyl)-N-(3,4-dihydroxybenzyl)acetamide
CAS:1808986-37-9
MF:C15H13Cl2NO3
MW:326.17
EINECS:
Product Categories:
Mol File:1808986-37-9.mol
Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- Structure
Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- Chemical Properties
Boiling point 608.9±55.0 °C(Predicted)
density 1.442±0.06 g/cm3(Predicted)
pka9.58±0.20(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- Usage And Synthesis
UsesERCC1-XPF-IN-2 is a potent ERCC1-XPF endonuclease inhibitor with an IC50 value of 0.6 μM. ERCC1-XPF-IN-2 shows activity in nucleotide excision repair, cisplatin enhancement and γH2AX assays[1].
References[1] Chapman TM, et al. Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF. Bioorg Med Chem Lett. 2015 Oct 1;25(19):4097-103. DOI:10.1016/j.bmcl.2015.08.031
Benzeneacetamide, 2,4-dichloro-N-[(3,4-dihydroxyphenyl)methyl]- Preparation Products And Raw materials
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