1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)-

Request For Quotation
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- manufacturers

  • (R)-TTBK1-IN-1
  • (R)-TTBK1-IN-1 pictures
  • $2500.00
  • 2026-07-15
  • CAS:2735015-59-3
  • Purity:
  • Supply Ability: 10g
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Basic information
Product Name:1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)-
Synonyms:1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)-;(R)-TTBK1-IN-1
CAS:2735015-59-3
MF:C18H19N5O2
MW:337.38
EINECS:
Product Categories:
Mol File:2735015-59-3.mol
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Structure
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Chemical Properties
Boiling point 557.8±60.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
pka12.91±0.29(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Usage And Synthesis
Uses(R)-TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor. (R)-TTBK1-IN-1 is an enantiomer of TTBK1-IN-1 (HY-134968). (R)-TTBK1-IN-1 can be used in the research of alzheimer’s disease and related tauopathies[1]. (R)-TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References[1] Halkina T, et, al. Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo. J Med Chem. 2021 May 13;64(9):6358-6380. DOI:10.1021/acs.jmedchem.1c00382
1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)- Preparation Products And Raw materials
Tag:1-Pentyn-3-ol, 1-[1-(2-amino-6-methoxy-4-pyrimidinyl)-1H-pyrrolo[3,2-c]pyridin-6-yl]-3-methyl-, (3R)-(2735015-59-3) Related Product Information
5-Pyrimidinecarboxamide, 2-[(3S)-3-amino-1-piperidinyl]-4-[[2,6-bis(1-methylethyl)-4-pyridinyl]amino]- 3-Amino-6-[4-[[4-[4-[1-[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]-1H-1,2,3-triazol-4-yl]butyl]-1-piperazinyl]sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide Levistilide A VERBENALIN 7-(6-Fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole Bepranemab