3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- manufacturers
- OXPHOS-IN-1
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- $1980.00
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2026-04-20
- CAS:2749554-48-9
- Purity:
- Supply Ability: 10g
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| | 3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- Basic information |
| | 3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- Chemical Properties |
| density | 1.40±0.1 g/cm3(Predicted) | | pka | 14.26±0.20(Predicted) |
| | 3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- Usage And Synthesis |
| Uses | OXPHOS-IN-1 (compound 2) is a oxidative phosphorylation (OXPHOS) inhibitor. OXPHOS-IN-1 inhibits the cells growth of MIA PaCa-2 and BxPC-3 cells with IC50s of 2.34 μM and 13.82 μM, respectively[1]. | | References | [1] Ding Xue, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022 Feb 24;65(4):3404-3419. DOI:10.1021/acs.jmedchem.1c01934 |
| | 3-Piperidinecarboxamide, 1-[[4-[(diethylamino)sulfonyl]phenyl]sulfonyl]-N-3-oxetanyl-, (3R)- Preparation Products And Raw materials |
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