YM 114

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Company Name: TargetMol Chemicals Inc.
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Email: marketing@targetmol.com
Products Intro: Product Name:YM 114;Kae 393;YM-114
CAS:153608-99-2
Package:100 mg;500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Products Intro: Product Name:YM 114
CAS:153608-99-2
Package:50mg;1980USD|100mg;2500USD|25mg;1520USD
Company Name: Suzhou Meishi Biotechnology Co., Ltd.  
Tel: 1173954148q
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Products Intro: Product Name:153608-99-2
CAS:153608-99-2
Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:YM 114
CAS:153608-99-2
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
Company Name: CHEMICAL LAND21  
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YM 114 Basic information
Product Name:YM 114
Synonyms:YM 114;Kae 393
CAS:153608-99-2
MF:C16H18ClN3O
MW:303.79
EINECS:
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Mol File:153608-99-2.mol
YM 114 Structure
YM 114 Chemical Properties
Safety Information
MSDS Information
YM 114 Usage And Synthesis
DescriptionYM 114 is a 5-HT(3) receptor anatagonist.
UsesYM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1].
References[1] Yamano M, et al. Characteristics of inhibitory effects of serotonin (5-HT)3-receptor antagonists, YM060 and YM114 (KAE-393), on the von Bezold-Jarisch reflex induced by 2-Methyl-5-HT, veratridine and electrical stimulation of vagus nerves in anesthetized rats. Jpn J Pharmacol. 1995 Dec;69(4):351-6. DOI:10.1254/jjp.69.351
YM 114 Preparation Products And Raw materials
Tag:YM 114(153608-99-2) Related Product Information
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