Company Name: |
Suzhou Meishi Biotechnology Co., Ltd.
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Tel: |
1173954148q |
Email: |
meishipharma@126.com |
Products Intro: |
Product Name:153608-99-2 CAS:153608-99-2 Purity:99% HPLC Package:1G;5G;10G;100G;1KG;
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:YM 114 CAS:153608-99-2 Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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Company Name: |
CHEMICAL LAND21
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Tel: |
82- 2 -783 - 8063 |
Email: |
sales21@chemicalland21.com |
Products Intro: |
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YM 114 manufacturers
- YM 114
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- $1980.00 / 50mg
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2024-10-24
- CAS:153608-99-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| YM 114 Chemical Properties |
| YM 114 Usage And Synthesis |
Description | YM 114 is a 5-HT(3) receptor anatagonist. | Uses | YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1]. | References | [1] Yamano M, et al. Characteristics of inhibitory effects of serotonin (5-HT)3-receptor antagonists, YM060 and YM114 (KAE-393), on the von Bezold-Jarisch reflex induced by 2-Methyl-5-HT, veratridine and electrical stimulation of vagus nerves in anesthetized rats. Jpn J Pharmacol. 1995 Dec;69(4):351-6. DOI:10.1254/jjp.69.351 |
| YM 114 Preparation Products And Raw materials |
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