PDE4B/7A-IN-2

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PDE4B/7A-IN-2 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
PDE4B/7A-IN-2 Basic information
Product Name:PDE4B/7A-IN-2
Synonyms:PDE4B/7A-IN-2
CAS:2511632-55-4
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
PDE4B/7A-IN-2 Structure
PDE4B/7A-IN-2 Chemical Properties
Safety Information
MSDS Information
PDE4B/7A-IN-2 Usage And Synthesis
Uses5-HT1A/5-HT7 receptor antagonist (5-HT1A Ki = 8 nM, Kb = 0.04 nM; 5-HT7 Ki = 451 nM, Kb = 460 nM) with PDE4B/PDE7A inhibitory activity (PDE4B IC50 = 80.4 μM; PDE7A IC50 = 151.3 μM) , its antidepressant like effect is stronger than that of escitalopram as a reference agent.
IC 50PDE4; PDE7
References[1] Jankowska A,et al. Novel anilide and benzylamide derivatives of arylpiperazinylalkanoic acids as 5-HT1A/5-HT7 receptor antagonists and phosphodiesterase 4/7 inhibitors with procognitive and antidepressant activity. Eur J Med Chem. 2020 Sep 1;201:112437. DOI:10.1016/j.ejmech.2020.112437
PDE4B/7A-IN-2 Preparation Products And Raw materials
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