Englumafusp

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Company Name: Wuhan Acumen Bio-Technology Co.,ltd  
Tel: 027-027-16602739303 16602739303
Email: 673003916@qq.com
Company Name: Wuhan Maixi Biotechnology Co., Ltd  
Tel: 18007167883 18007167883
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Englumafusp Basic information
Product Name:Englumafusp
Synonyms:
CAS:2417199-08-5
MF:
MW:0
EINECS:
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Mol File:Mol File
Englumafusp Structure
Englumafusp Chemical Properties
Safety Information
MSDS Information
Englumafusp Usage And Synthesis
UsesEnglumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells[1].
References[1] Antonio Tapia-Galisteo, et al. Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies. J Hematol Oncol. 2023 Jul 27;16(1):83. DOI:10.1186/s13045-023-01482-w
[2] George Fromm, et al. Reconciling intrinsic properties of activating TNF receptors by native ligands versus synthetic agonists. Front Immunol. 2023 Sep 19:14:1236332. DOI:10.3389/fimmu.2023.1236332
Englumafusp Preparation Products And Raw materials
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