1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate

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1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Suppliers list
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1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate manufacturers

  • Enpp-1-IN-16
  • Enpp-1-IN-16 pictures
  • $49.00
  • 2026-05-11
  • CAS:2289739-47-3
  • Purity: 99.87%
  • Supply Ability: 10g
1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Basic information
Product Name:1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate
Synonyms:1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate;Enpp-1-IN-16
CAS:2289739-47-3
MF:C23H32N4O4
MW:428.53
EINECS:
Product Categories:
Mol File:2289739-47-3.mol
1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Structure
1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Chemical Properties
Boiling point 573.2±50.0 °C(Predicted)
density 1.24±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka9.69±0.70(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Usage And Synthesis
UsesEnpp-1-IN-16 (compound 54) is an ENPP1 inhibitor. Enpp-1-IN-16 has the potential to study cancer, especially in cases of high ENPP1 expression or elevated cytoplasmic DNA levels. Enpp-1-IN-16 can also be used in other diseases mediated by ENPP1, such as bacterial or viral infections, insulin resistance and type II diabetes, chondrocalcinosis and osteoarthritis, calcium pyrophosphate deposition disorder (CPPD), low Phosphatase disease and soft tissue calcification disorders[1].
References[1] Derek A Cogan, et al. Imino sulfanone inhibitors of enpp1. WO2021225969A1.
1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate Preparation Products And Raw materials
Tag:1,1-Dimethylethyl 8-(6,7-dimethoxy-4-quinazolinyl)-2,8-diazaspiro[4.5]decane-2-carboxylate(2289739-47-3) Related Product Information
tert-Butyl 4-(quinazolin-4-ylamino)piperidine-1-carboxylate tert-Butyl N-[(3S)-1-(quinazolin-4-yl)pyrrolidin-3-yl]carbamate Terazosin impurity tert-Butyl N-{[1-(quinazolin-4-yl)piperidin-4-yl]methyl}carbamate N-[(3R)-Pyrrolidin-3-yl]pyridin-2-amine dihydrochloride 1-Piperidinecarboxylic acid, 4-[(2-chloro-7-methoxy-4-quinazolinyl)amino]-, 1,1-dimethylethyl ester