[1,1′-Biphenyl]-3-sulfonyl fluoride, 3′,5′-difluoro-4′-[(2S)-2-[(2H-tetrazol-5-ylamino)carbonyl]hexyl]- manufacturers
- WM-586
-
- $2970.00
-
2026-07-15
- CAS:2894832-05-2
- Purity:
- Supply Ability: 10g
|
| | [1,1′-Biphenyl]-3-sulfonyl fluoride, 3′,5′-difluoro-4′-[(2S)-2-[(2H-tetrazol-5-ylamino)carbonyl]hexyl]- Basic information |
| | [1,1′-Biphenyl]-3-sulfonyl fluoride, 3′,5′-difluoro-4′-[(2S)-2-[(2H-tetrazol-5-ylamino)carbonyl]hexyl]- Chemical Properties |
| density | 1.422±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | form | Solid | | pka | 3.55±0.10(Predicted) | | color | White to off-white |
| | [1,1′-Biphenyl]-3-sulfonyl fluoride, 3′,5′-difluoro-4′-[(2S)-2-[(2H-tetrazol-5-ylamino)carbonyl]hexyl]- Usage And Synthesis |
| Uses | WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC. WM-586 specifically decreases cellular WDR5 and MYC interaction with the IC50 of 101 nM in HTRF assay[1]. | | References | [1] Ding J, et al. Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chem Biol. 2023 Jan 20;18(1):34-40. DOI:10.1021/acschembio.2c00843 |
| | [1,1′-Biphenyl]-3-sulfonyl fluoride, 3′,5′-difluoro-4′-[(2S)-2-[(2H-tetrazol-5-ylamino)carbonyl]hexyl]- Preparation Products And Raw materials |
|