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5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine Suppliers list
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:RS 15385-197
CAS:119813-87-5
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
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| Company Name: |
CHEMICAL LAND21
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| Tel: |
82- 2 -783 - 8063 |
| Email: |
sales21@chemicalland21.com |
| Products Intro: |
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5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine manufacturers
- RS 15385-197
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- $1520.00 / 25mg
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2025-08-21
- CAS:119813-87-5
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine Basic information |
| Product Name: | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine | | Synonyms: | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine;6H-Isoquino[2,1-g][1,6]naphthyridine, 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-, (8aR,12aS,13aS)-rel-;RS 15385197,RS 15385 197 | | CAS: | 119813-87-5 | | MF: | C18H26N2O3S | | MW: | 350.48 | | EINECS: | | | Product Categories: | | | Mol File: | 119813-87-5.mol |  |
| | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine Chemical Properties |
| Boiling point | 507.5±60.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | pka | 7.70±0.20(Predicted) |
| | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine Usage And Synthesis |
| Description | RS 15385-197 is a potent and selective alpha 2-adrenoceptor antagonist. | | Uses | rel-Delequamine (rel-RS-15385-197) is an orally active, brain-penetrant, potent and selective M2-adrenoceptor antagonist and α2-adrenoceptor antagonist. rel-Delequamine has a pKi of 9.45 for α2-adrenoceptors in the rat cortex. rel-Delequamine augments K+-evoked release of noradrenaline with an EC50 of 1 nM[1]. | | References | [1] Brown CM, et al. The pharmacology of RS-15385-197, a potent and selective alpha 2-adrenoceptor antagonist. Br J Pharmacol. 1993 Feb;108(2):516-25. DOI:10.1111/j.1476-5381.1993.tb12834.x
[2] Redfern WS, et al. Modulation of central noradrenergic function by RS-15385-197. Br J Pharmacol. 1993 Feb;108(2):526-33. DOI:10.1111/j.1476-5381.1993.tb12835.x |
| | 5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-methoxy-12-(methylsulfonyl)-6H-isoquino(2,1-g)(1,6)naphthyridine Preparation Products And Raw materials |
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