QR-6401 manufacturers
- QR-6401
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- $2180.00
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2026-07-27
- CAS:2845096-18-4
- Purity:
- Supply Ability: 10g
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| | QR-6401 Basic information |
| | QR-6401 Chemical Properties |
| | QR-6401 Usage And Synthesis |
| Uses | QR-6401 is an orally active and selective macrocyclic CDK2 inhibitor with IC50 values of 0.37, 10, 22, 34 and 45 nM for CDK2/E1, CDK9/T1, CDK1/A2, CDK6/D3 and CDK4/D1, respectively. QR-6401 has potent antitumor activity in an OVCAR3 ovarian cancer xenograft model. QR-6401 has the potential to be used in the study of cancer[1]. | | References | [1] Yu Y, et al. Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design. ACS Med Chem Lett. 2023 Feb 8;14(3):297-304. DOI:10.1021/acsmedchemlett.2c00515 |
| | QR-6401 Preparation Products And Raw materials |
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