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| | Antiproliferative agent-33 Basic information |
| | Antiproliferative agent-33 Chemical Properties |
| Boiling point | 479.851±47.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.056±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 5.371±0.10(predicted) |
| | Antiproliferative agent-33 Usage And Synthesis |
| Uses | Antiproliferative agent-33 (Compound 2g) is an anti-proliferative, antifungal, and antibacterial agent. Antiproliferative agent-33 inhibits MDA-MB-231 cell proliferation (IC50: 16.38 μM). Antiproliferative agent-33 inhibits gram-negative bacteria growth, and inhibits S. faecalis with an MIC value of 8 μg/mL[1]. | | References | [1] Phan NK, et al. Exploration of Remarkably Potential Multitarget-Directed N-Alkylated-2-(substituted phenyl)-1H-benzimidazole Derivatives as Antiproliferative, Antifungal, and Antibacterial Agents. ACS Omega. 2023 Jul 28;8(31):28733-28748. DOI:10.1074/jbc.RA118.007129 |
| | Antiproliferative agent-33 Preparation Products And Raw materials |
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