4-(4-HYDROXYPHENYL)BUTANOIC ACID manufacturers
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| | 4-(4-HYDROXYPHENYL)BUTANOIC ACID Basic information |
| | 4-(4-HYDROXYPHENYL)BUTANOIC ACID Chemical Properties |
| Melting point | 110-111 °C | | Boiling point | 128-200 °C(Press: 0.4 Torr) | | density | 1.214±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | Chloroform (Slightly), DMSO (slightly) | | pka | 4.78±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | 4-(4-HYDROXYPHENYL)BUTANOIC ACID Usage And Synthesis |
| Uses | 4-Carboxypropylphenol is a bacterial chlorophyll derivative. | | Synthesis | 4-(4-Methoxyphenyl)butyric acid (25g, 129mmol) was dissolved in 48% HBr (125ml) and AcOH (125ml). The resulting solution was heated at 150°C overnight. The resulting mixture was concentrated in vacuo and the residue was dissolved in EtOAc (500ml). The solution was washed with water (500ml), dried (MgSO4) and concentrated to give 4-(4-hydroxyphenyl)butanoic acid as a tan solid. | | References | [1] Bioorganic and Medicinal Chemistry Letters, 2001, vol. 11, # 4, p. 509 - 513
[2] Journal of Natural Products, 2017, vol. 80, # 5, p. 1623 - 1630
[3] Organic Process Research and Development, 2004, vol. 8, # 4, p. 670 - 673
[4] Patent: EP2388247, 2011, A2. Location in patent: Page/Page column 12
[5] Patent: US2011/288133, 2011, A1. Location in patent: Page/Page column 10 |
| | 4-(4-HYDROXYPHENYL)BUTANOIC ACID Preparation Products And Raw materials |
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