HDAC/JAK/BRD4-IN-1

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HDAC/JAK/BRD4-IN-1 Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: Shanghai Tachizaki Biomedical Research Center  
Tel: 18014399201
Email: sales@chemlab-tachizaki.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

HDAC/JAK/BRD4-IN-1 manufacturers
HDAC/JAK/BRD4-IN-1 Basic information
Product Name:HDAC/JAK/BRD4-IN-1
Synonyms:HDAC/JAK/BRD4-IN-1;Benzamide, N-hydroxy-4-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]-
CAS:2755325-84-7
MF:C24H28N6O3
MW:448.52
EINECS:
Product Categories:
Mol File:2755325-84-7.mol
HDAC/JAK/BRD4-IN-1 Structure
HDAC/JAK/BRD4-IN-1 Chemical Properties
density 1.311±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
form Solid
pka9.01±0.10(predicted)
color Off-white to light yellow
Safety Information
MSDS Information
HDAC/JAK/BRD4-IN-1 Usage And Synthesis
UsesHDAC/JAK/BRD4-IN-1(compound 25ap) is a potent HDAC/JAK/BRD4 triple inhibitor. HDAC/JAK/BRD4-IN-1 inhibit cell growth and induces apoptosis in MDA-MB-231 cells, and shows anticancer activity in vivo[1].
References[1] Zhao C, et al. Discovery of Novel Fedratinib-Based HDAC/JAK/BRD4 Triple Inhibitors with Remarkable Antitumor Activity against Triple Negative Breast Cancer [published online ahead of print, 2023 Oct 5]. J Med Chem. 2023;10.1021/acs.jmedchem.3c01242. DOI:10.1021/acs.jmedchem.3c01242
HDAC/JAK/BRD4-IN-1 Preparation Products And Raw materials
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