HSD17B13-IN-99

Request For Quotation
HSD17B13-IN-99 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
HSD17B13-IN-99 Basic information
Product Name:HSD17B13-IN-99
Synonyms:HSD17B13-IN-99;2-Pyridinecarboxamide, N-[3,4-dihydro-3-[2-(2-methoxyphenyl)ethyl]-4-oxo-5-quinazolinyl]-5-hydroxy-6-(trifluoromethyl)-
CAS:2849338-46-9
MF:C24H19F3N4O4
MW:484.43
EINECS:
Product Categories:
Mol File:2849338-46-9.mol
HSD17B13-IN-99 Structure
HSD17B13-IN-99 Chemical Properties
density 1.42±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka10.50±0.20(predicted)
Safety Information
MSDS Information
HSD17B13-IN-99 Usage And Synthesis
UsesHSD17B13-IN-99 (Compound 6) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of < 0.1 μM for estradiol. HSD17B13-IN-99 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
References[1] Joshua Odingo, et al. Hydroxypyridine hsd17b13 inhibitors and uses thereof. U.S., WO2022216626. 2022-10-13.
HSD17B13-IN-99 Preparation Products And Raw materials
Tag:HSD17B13-IN-99(2849338-46-9) Related Product Information
2-Thiophenecarboxamide, 3-[(3-chloro-4-hydroxybenzoyl)amino]-N-[2-(2-methoxyphenyl)ethyl]- 6-Bromocoumarin 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulphonyl)benzoic acid FXRHSD17B13 modulator 1 HSD17B13-IN-43 Phosphinic acid, P,P-bis(1-aziridinyl)-, (1S)-1-[3-[3-[(dimethylamino)carbonyl]phenoxy]-4-nitrophenyl]ethyl ester