Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]-

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Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
Products Intro: Product Name:CLZX-205
CAS:3033694-01-5
Package:50mg;10mg
Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Basic information
Product Name:Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]-
Synonyms:Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]-
CAS:3033694-01-5
MF:C26H30N8O
MW:470.57
EINECS:
Product Categories:
Mol File:3033694-01-5.mol
Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Structure
Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Chemical Properties
Boiling point 679.8±55.0 °C(predicted)
density 1.31±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka8.06±0.10(predicted)
Safety Information
MSDS Information
Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Usage And Synthesis
UsesCLZX-205 (compound C-7) is a selective inhibitor of CDK9, with the IC50 of 2.9 nM. CLZX-205 plays an important role in cancer research[1].
IC 50CDK9: 2.9 nM (IC50)
References[1] Ye Zhong, et al. Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation. J Med Chem. 2024 Mar 28;67(6):4739-4756. DOI:10.1021/acs.jmedchem.3c02329
Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]- Preparation Products And Raw materials
Tag:Methanone, (hexahydro-4-methyl-1H-1,4-diazepin-1-yl)[2-[[4-[1-(1-methylethyl)-1H-benzotriazol-6-yl]-2-pyridinyl]amino]-4-pyridinyl]-(3033694-01-5) Related Product Information