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| | SUC-ALA-PHE-LYS-AMC Basic information |
| Product Name: | SUC-ALA-PHE-LYS-AMC | | Synonyms: | SUC-ALA-PHE-LYS-AMC;Suc-AFK-AMC;N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide;L-Lysinamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | | CAS: | 73207-91-7 | | MF: | C32H39N5O8 | | MW: | 621.68 | | EINECS: | | | Product Categories: | | | Mol File: | 73207-91-7.mol |  |
| | SUC-ALA-PHE-LYS-AMC Chemical Properties |
| Boiling point | 1039.6±65.0 °C(Predicted) | | density | 1.302±0.06 g/cm3(Predicted) | | form | Solid | | pka | 4.69±0.10(Predicted) | | color | White to off-white | | Sequence | {Suc-Ala}-Phe-{Lys-AMC} |
| | SUC-ALA-PHE-LYS-AMC Usage And Synthesis |
| Uses | Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K[1][2]. | | References | [1] P A Pierzchala, et al. A new fluorogenic substrate for plasmin. Biochem J. 1979 Dec 1;183(3):555-9. DOI:10.1042/bj1830555
[2] Marion G Gtz, et al. Aza-peptidyl Michael Acceptors. A New Class of Potent and Selective Inhibitors of Asparaginyl Endopeptidases (Legumains) from Evolutionarily Diverse Pathogens. J Med Chem. 2008 May 8;51(9):2816-32. DOI:10.1021/jm701311r |
| | SUC-ALA-PHE-LYS-AMC Preparation Products And Raw materials |
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