- 3,5-Dichloropyridazine
-
- $0.00 / 25kg
-
2025-12-05
- CAS:1837-55-4
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kg
- 3,5-Dichloropyridazine
-
- $1.10 / 1g
-
2025-11-18
- CAS:1837-55-4
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
- 3,5-Dichloropyridazine
-
- $10.00 / 1kg
-
2025-05-23
- CAS:1837-55-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20 ton
|
| | 3,5-Dichloropyridazine Basic information |
| | 3,5-Dichloropyridazine Chemical Properties |
| Melting point | 60.0 to 64.0 °C | | Boiling point | 280.8±20.0 °C(Predicted) | | density | 1.493±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Sparingly), Methanol (Slightly) | | form | Solid | | pka | -0.25±0.10(Predicted) | | color | Yellow to Dark Orange | | InChI | InChI=1S/C4H2Cl2N2/c5-3-1-4(6)8-7-2-3/h1-2H | | InChIKey | JZSAUQMXKHBZEO-UHFFFAOYSA-N | | SMILES | C1(Cl)=NN=CC(Cl)=C1 |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | WGK 3 | | HS Code | 29339900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 3,5-Dichloropyridazine Usage And Synthesis |
| Chemical Properties | Yellow solid powder. | | Uses | 3,5-Dichloropyridazine used in the treatment of asthma and allergy. Potential for antinociceptive and antiinflammatory effects | | Uses | 3,5-Dichloropyridazine acts as a novel histamine H4 antagonist used in the treatment of asthma and allergy. Potential for antinociceptive and antiinflammatory effects. | | Definition | ChEBI: 3,5-Dichloropyridazine is a member of pyridazines. | | Preparation | Preparation of 3,5-Dichloropyridazine:
2,4,4,4-Tetrachlorocrotonaldehyde is dissolved in a solvent, and a mixture of semicarbazide hydrochloride, water, and solvent is added dropwise under controlled temperature conditions. The reaction is stirred for 5 hours. Afterward, the reaction mixture is concentrated under reduced pressure to remove the solvent. Water is added, and the temperature is lowered to 5°C, allowing a solid to precipitate. The solid is filtered and recrystallized using a dichloromethane/petroleum ether mixture, yielding 3,5-dichloropyridazine as a white crystalline solid. | | Application | 3,5-Dichloropyridazine can be used as a pharmaceutical reaction intermediate, for example, in the preparation of the compound 3-chloro-5-aminopyridazine. These compounds are commonly used chemical synthesis intermediates and have been widely applied in the research and development of drugs and pesticides in recent years, such as anticancer drugs (US2004/54186) and plant growth regulators (US1988/4728355). |
| | 3,5-Dichloropyridazine Preparation Products And Raw materials |
|