3-Amino-5-bromo-2-chloropyridine

3-Amino-5-bromo-2-chloropyridine Suppliers list

Company Name:	Henan Fengda Chemical Co., Ltd
Tel:	+86-371-86557731 +86-13613820652
Email:	info@fdachem.com
Products Intro:	Product Name:3-Amino-5-bromo-2-chloropyridine CAS:588729-99-1 Purity:99%, 99.5% Sublimated Package:1KG;200USD\|100KG;1USD

Company Name:	Frapp's ChemicalNFTZ Co., Ltd.
Tel:	+86 (576) 8169-6106
Email:	sales@frappschem.com
Products Intro:	Product Name:2-Chloro-3-amino-5-bromopyridine CAS:588729-99-1

Company Name:	Capot Chemical Co.,Ltd.
Tel:	+86-（0）57185586718; +8613336195806
Email:	sales@capot.com
Products Intro:	Product Name:3-Amino-5-bromo-2-chloropyridine CAS:588729-99-1 Purity:98%(Min,GC) Package:1G;1KG;100KG

Company Name:	Henan Tianfu Chemical Co.,Ltd.
Tel:	+86-0371-55170693 +86-19937530512
Email:	info@tianfuchem.com
Products Intro:	Product Name:588729-99-1 2-Chloro-3-amino-5-bromopyridine C5H4BrClN2 CAS:588729-99-1 Purity:99% Package:25KG;5KG;1KG

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:2-Chloro-3-amino-5-bromopyridine CAS:588729-99-1 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G

3-Amino-5-bromo-2-chloropyridine manufacturers

3-Amino-5-bromo-2-chloropyridine Basic information

Product Name:	3-Amino-5-bromo-2-chloropyridine
Synonyms:	5-BROMO-2-CHLORO-3-PYRIDINAMINE;5-BROMO-2-CHLORO-PYRIDIN-3-YLAMINE;5-BROMO-2-CHLOROPYRIDIN-3-AMINE;3-AMINO-5-BROMO-2-CHLOROPYRIDINE;3-Amino-5-bromo-2-chloropyridi;3-Amino-5-Bromo-2-Chloropyrid ;2-Chloro-3-amino-5-bromopyridine;3-Amino-5-bromo-2-chL
CAS:	588729-99-1
MF:	C5H4BrClN2
MW:	207.46
EINECS:	675-552-4
Product Categories:	blocks;Bromides;Pyridines;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;pharmacetical;Pyridine series;Amines;Pyridines ,Halogenated Heterocycles
Mol File:	588729-99-1.mol

3-Amino-5-bromo-2-chloropyridine Chemical Properties

Melting point	129-132℃
Boiling point	296.8±35.0 °C(Predicted)
density	1.834±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	powder to crystal
pka	0.03±0.10(Predicted)
color	White to Orange to Green
λmax	314nm(EtOH)(lit.)
InChI	InChI=1S/C5H4BrClN2/c6-3-1-4(8)5(7)9-2-3/h1-2H,8H2
InChIKey	ZSEZSALOLWCCGT-UHFFFAOYSA-N
SMILES	C1(Cl)=NC=C(Br)C=C1N
CAS DataBase Reference	588729-99-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi,T
Risk Statements	25-37/38-41-22
Safety Statements	26-39-45
RIDADR	2811
WGK Germany	3
HazardClass	IRRITANT
PackingGroup	Ⅲ
HS Code	29333990
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3

MSDS Information

3-Amino-5-bromo-2-chloropyridine Usage And Synthesis

Chemical Properties	Colorless solid
Uses	3-Amino-5-bromo-2-chloropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis	67443-38-3 588729-99-1 Step 1: 2-Chloro-3-nitro-5-bromopyridine (2.38 g, 10 mmol) was dissolved in methanol (50 mL) and Raney nickel (0.5 g) was added. The reaction mixture was stirred overnight under hydrogen atmosphere. Upon completion of the reaction, the Raney nickel was removed by filtration and the filtrate was concentrated to afford 2-chloro-3-amino-5-bromopyridine (2.08 g, 100% yield), which could be used in subsequent reactions without further purification. Mass spectrum (ESI) m/z: 208.9 [M + 1].
References	[1] Patent: EP2952510, 2015, A1. Location in patent: Paragraph 0146 [2] Patent: WO2008/157191, 2008, A2. Location in patent: Page/Page column 75 [3] Patent: WO2008/150827, 2008, A1. Location in patent: Page/Page column 69 [4] Journal of Heterocyclic Chemistry, 2003, vol. 40, # 2, p. 261 - 268 [5] Patent: US2012/238587, 2012, A1. Location in patent: Page/Page column 17

3-Amino-5-bromo-2-chloropyridine Preparation Products And Raw materials

Raw materials	5-Bromo-2-chloro-3-nitropyridine-->2-Amino-5-bromo-N,N-dimethylpyridine-3-sulfonamide-->Bis(pinacolato)diboron-->Hydrogen-->Nickel-->Methanol
Preparation Products	5-BROMO-N-(TERT-BUTYL)-2-(DIMETHYLAMINO)PYRIDINE-3-SULFONAMIDE-->N-(5-broMo-2-chloropyridin-3-yl)-2,4-difluorobenzenesulfonaMide

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