1-(DIETHOXYMETHYL)IMIDAZOLE manufacturers
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| | 1-(DIETHOXYMETHYL)IMIDAZOLE Basic information |
| | 1-(DIETHOXYMETHYL)IMIDAZOLE Chemical Properties |
| Boiling point | 52 °C(Press: 0.02 Torr) | | density | 1.041 g/mL at 20 °C (lit.) | | refractive index | n20/D 1.464 | | Fp | 112℃ | | storage temp. | 2-8°C | | pka | 6.13±0.20(Predicted) | | form | liquid | | BRN | 908482 | | InChI | 1S/C8H14N2O2/c1-3-11-8(12-4-2)10-6-5-9-7-10/h5-8H,3-4H2,1-2H3 | | InChIKey | NNQBAGFIYBBAFL-UHFFFAOYSA-N | | SMILES | CCOC(OCC)n1ccnc1 |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | F | 10-21 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 1-(DIETHOXYMETHYL)IMIDAZOLE Usage And Synthesis |
| Uses | 1-(Diethoxymethyl)imidazole may be used in the preparation of various hydroxy- and amino-functionalized imidazoles, via isoprene-mediated lithiation followed by reaction with an electrophile. | | General Description | 1-(Diethoxymethyl)imidazole is an orthoamide protected imidazole. The dianion reacts selectively at the 2 position 1-(Diethoxymethyl)imidazole is a 1-substituted imidazoles. Isoprene-mediated lithiation of 1-(diethoxymethyl)imidazole, leads to the preparation of the corresponding 2-lithio intermediate, which reacts with different electrophiles to afford 2-functionalised imidazoles. |
| | 1-(DIETHOXYMETHYL)IMIDAZOLE Preparation Products And Raw materials |
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