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| | Ethyl dichlorophosphate Basic information |
| | Ethyl dichlorophosphate Chemical Properties |
| Melting point | -42.5 °C | | Boiling point | 60-65 °C10 mm Hg(lit.) | | density | 1.373 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.434(lit.) | | Fp | >230 °F | | storage temp. | Inert atmosphere,Room Temperature | | form | Liquid | | color | Clear colorless to pale brown | | InChI | InChI=1S/C2H5Cl2O2P/c1-2-6-7(3,4)5/h2H2,1H3 | | InChIKey | YZBOZNXACBQJHI-UHFFFAOYSA-N | | SMILES | P(Cl)(Cl)(OCC)=O | | CAS DataBase Reference | 1498-51-7(CAS DataBase Reference) | | NIST Chemistry Reference | Ethyl dichlorophosphate(1498-51-7) | | EPA Substance Registry System | Ethyl dichlorophosphate (1498-51-7) |
| Hazard Codes | T+,C,Xi | | Risk Statements | 26-34-22 | | Safety Statements | 26-28-36/37/39-45 | | RIDADR | UN 3390 6.1/PG 1 | | WGK Germany | 3 | | RTECS | TD4390000 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29209090 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 2 Inhalation
Acute Tox. 3 Oral
Eye Dam. 1
Skin Corr. 1B | | Hazardous Substances Data | 1498-51-7(Hazardous Substances Data) |
| | Ethyl dichlorophosphate Usage And Synthesis |
| Chemical Properties | Light Yellow Liquid | | Uses | Ethyl Dichlorophosphate is an intermediate used in the synthesis of b-D-2'-deoxy-2'-a-fluoro-2'-b-C-methyluridine nucleotide prodrug (PSI-7977) for treatment of hepatitis C virus. It is also used to prepare dialkylphosphocholines with antiprotozoal, antifungal and antitumor activities. | | General Description | Ethyl dichlorophosphate is strongly irritating to skin. Ethyl dichlorophosphate may cause visible destruction or irreversible alterations in human skin tissue at the site of contact. Ethyl dichlorophosphate is very toxic by ingestion, inhalation, or by skin absorption. Ethyl dichlorophosphate may be combustible though Ethyl dichlorophosphate may require some effort to ignite. | | Air & Water Reactions | Reacts with water to form hydrogen chloride(hydrochloric acid) | | Reactivity Profile | Organophosphates, such as Ethyl dichlorophosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | | Health Hazard | Inhalation of vapor irritates nose and throat. Contact with liquid causes severe burns of eyes and skin. Ingestion causes severe burns of mouth and stomach. | | Safety Profile | A corrosive material
that is very toxic to tissue. A severe eye,
skin, and mucous membrane irritant. When
heated to decomposition it emits very toxic
fumes of Cland POx. |
| | Ethyl dichlorophosphate Preparation Products And Raw materials |
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