5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE manufacturers
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| | 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Basic information |
| | 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Chemical Properties |
| Melting point | 70-73 °C(lit.) | | Boiling point | 137 °C / 15mmHg | | density | 1.250±0.06 g/cm3(Predicted) | | storage temp. | RT, stored under nitrogen | | form | powder to crystal | | pka | 9.84±0.23(Predicted) | | color | White to Light yellow | | InChI | InChI=1S/C9H9ClO2/c1-5-3-9(12)7(6(2)11)4-8(5)10/h3-4,12H,1-2H3 | | InChIKey | HDUSGGZSLVCDKY-UHFFFAOYSA-N | | SMILES | C(=O)(C1=CC(Cl)=C(C)C=C1O)C | | CAS DataBase Reference | 28480-70-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 2914.50.3000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Usage And Synthesis |
| Uses | 5′-Chloro-2′-hydroxy-4′-methylacetophenone (5-chloro-2-hydroxy-4-methylacetophenone) may be used in the preparation of the following:
- chalcones, required for the synthesis of novel pyrazoline derivatives
- 5′-chloro-2′-hydroxy-4′-methyl-3-(2′′-thienyl)acrylophenone
- 6-chloro-3-hydroxy-7-methyl-2-(2-thienyl)-4H-chromen-4-one, a complexing agent used for the spectrophotometric determination of vanadium(V)
| | Preparation | Preparation by reaction of acetic acid on 4-chloro-3- methylphenol with boron trifluoride at 70–100° (80–85%). | | General Description | 5′-chloro-2′-hydroxy-4′-methylacetophenone (5-Chloro-2-hydroxy-4-methylacetophenone) is a hydroxylated aromatic acetophenone. Its iodination by pyridinium iodochloride has been reported to afford 5-chloro-2-hydroxy-3-iodo-4-methylacetophenone. |
| | 5'-CHLORO-2'-HYDROXY-4'-METHYLACETOPHENONE Preparation Products And Raw materials |
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