- 3-Fluoro-2-nitropyridine
-
- $1.10 / 1g
-
2025-11-18
- CAS:54231-35-5
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons min
|
| | 3-Fluoro-2-nitropyridine Basic information |
| | 3-Fluoro-2-nitropyridine Chemical Properties |
| Melting point | 35°C | | Boiling point | 255.8±20.0 °C(Predicted) | | density | 1.439±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | powder to crystal | | pka | -5.01±0.22(Predicted) | | color | Light yellow to Yellow to Orange | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C5H3FN2O2/c6-4-2-1-3-7-5(4)8(9)10/h1-3H | | InChIKey | IJVFHCSUEBAAOZ-UHFFFAOYSA-N | | SMILES | C1([N+]([O-])=O)=NC=CC=C1F | | CAS DataBase Reference | 54231-35-5(CAS DataBase Reference) |
| Hazard Codes | Xi,C | | Risk Statements | 34 | | Safety Statements | 36/37/39-45-24/25 | | RIDADR | UN3261 | | TSCA | N | | HazardClass | IRRITANT | | HS Code | 29339900 |
| | 3-Fluoro-2-nitropyridine Usage And Synthesis |
| Chemical Properties | light brown crystal powder or liquid | | Uses | A specialty product for proteomics research applications. | | Synthesis | A solution of sodium nitrite (20 g, 288 mmol) in water (40 mL) was added dropwise to a solution of 3-amino-2-nitropyridine (40 g, 288 ) in 34% fluoroboric acid (140 mL).
mmol) in 34% fluoboric acid (140 mL) in a stirred mixture. The temperature was maintained between -8 ??C and -2 ??C during the addition.
After 0.5 h, the suspension was filtered and the solid was washed with 34% fluoboric acid (35 mL), ether (80 mL), and dried at room temperature under high vacuum for 12 h to give 52
g of fluoroborate as an orange-brown solid salt. The dried solid is decomposed by heating to 120 ??C.
After decomposition, the remaining oil was treated with a 10% sodium bicarbonate (80 mL) solution and the mixture was extracted with dichloromethane.
The combined extracts were dried with sodium sulfate, filtered and the solvent removed under reduced pressure to give the title compound as a light yellow solid. |
| | 3-Fluoro-2-nitropyridine Preparation Products And Raw materials |
|