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7-Octynoic acid

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Company Name: Accela ChemBio Inc.
Tel: +1-858-6993322
Email: info@accelachem.com
Products Intro: Product Name:7-Octynoic Acid
CAS:10297-09-3
Purity:>97% Package:0.1g;0.25g;1g;5g;10g;25g
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:7-Octynoic acid
CAS:10297-09-3
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Alfa Chemistry
Tel: +1-5166625404;
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Products Intro: Product Name:7-Octynoic acid
CAS:10297-09-3
Purity:98%+
Company Name: BTC pharm India
Tel: +918790379245
Email: banny.janga@btcpharm.com
Products Intro: Product Name:7-Octynoic acid
CAS:10297-09-3
Purity:98+ Package:5 kg, 25 kg, 100 kg and 1 MT
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:7-Octynoic acid
CAS:10297-09-3
Package:100mg;

7-Octynoic acid manufacturers

  • 7-Octynoic acid
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  • $0.00 / 100mg
  • 2026-04-13
  • CAS:10297-09-3
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  • Supply Ability: 10g
7-Octynoic acid Basic information
Product Name:7-Octynoic acid
Synonyms:7-Octynoic acid;oct-7-ynoic acid;WJBHDZBQZOMDFF-UHFFFAOYSA-N
CAS:10297-09-3
MF:C8H12O2
MW:140.18
EINECS:
Product Categories:
Mol File:10297-09-3.mol
7-Octynoic acid Structure
7-Octynoic acid Chemical Properties
Melting point 19°C
Boiling point 290.64°C (rough estimate)
density 1.0450 (rough estimate)
refractive index 1.4502
solubility DMSO: 150 mg/mL (1070.05 mM)
pka4.74±0.10(Predicted)
form Liquid
color Colorless to light pink
Water Solubility Water: 5 mg/mL (35.67 mM)
Safety Information
MSDS Information
7-Octynoic acid Usage And Synthesis
Uses7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. 7-Octynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
DefinitionChEBI: 7-octynoic acid is a medium-chain fatty acid.
IC 50Alkyl-Chain
References[1] Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17. DOI:10.1016/j.ccell.2019.10.002
7-Octynoic acid Preparation Products And Raw materials
Preparation Products7-OCTYN-1-OL-->7-Octynoic acid methyl ester
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