- Noreugenin
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- $52.00
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2026-06-02
- CAS:1013-69-0
- Purity: 99.57%
- Supply Ability: 10g
- Noreugenin
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- $9.80
-
2020-02-07
- CAS:1013-69-0
- Min. Order: 1KG
- Purity: ＞98%HPLC
- Supply Ability: 20 tons
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| | 2-Methyl-5,7-dihydroxychromone Basic information |
| Product Name: | 2-Methyl-5,7-dihydroxychromone | | Synonyms: | 2-Methyl-5,7-dihydroxy-4H-1-benzopyran-4-one;2-Methyl-5,7-dihydroxychromone;5,7-Dihydroxy-2-methyl-4H-1-benzopyran-4-one;reugenin;4H-1-Benzopyran-4-one,5,7-dihydroxy-2-methyl-;5,7-dihydroxy-2-methylchromen-4-one;Noreugenin, 10 mM in DMSO;Dihydroxy methyl chromone(DHMC) | | CAS: | 1013-69-0 | | MF: | C10H8O4 | | MW: | 192.17 | | EINECS: | | | Product Categories: | | | Mol File: | 1013-69-0.mol |  |
| | 2-Methyl-5,7-dihydroxychromone Chemical Properties |
| Melting point | 279 °C | | Boiling point | 394.6±42.0 °C(Predicted) | | density | 1.456±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (1300.93 mM); Water: < 0.1 mg/mL (insoluble) | | form | Solid | | pka | 6.58±0.40(Predicted) | | color | White to off-white | | Cosmetics Ingredients Functions | SKIN CONDITIONING
ANTIOXIDANT | | InChI | InChI=1S/C10H8O4/c1-5-2-7(12)10-8(13)3-6(11)4-9(10)14-5/h2-4,11,13H,1H3 | | InChIKey | NCUJRUDLFCGVOE-UHFFFAOYSA-N | | SMILES | C1(C)OC2=CC(O)=CC(O)=C2C(=O)C=1 |
| | 2-Methyl-5,7-dihydroxychromone Usage And Synthesis |
| Uses | Noreugenin, 5,7-dihydroxy-2-methyl-4H-chromen-4-one, is a new chromone from Aloe arborescens. (Amaryllidaceae)[1]. | | Definition | ChEBI: Noreugenin is a member of the class of chromones in which the 1,4-benzopyrone skeleton is substituted with a methyl group at position 2 and with hydroxy groups at positions 5 and 7. A natural product, it is found in Pisonia aculeata. It has a role as a plant metabolite. It is a member of chromones and a member of resorcinols. It is a conjugate acid of a noreugenin(1-). | | Synthesis | The general procedure for the synthesis of 5,7-dihydroxy-2-methyl-4H-benzopyran-4-one from the compound (CAS:1162-81-8) is as follows: 2-methyl-3-acetyl-5,7-diacetoxychromanone (15.9 g, 0.05 mol) was placed in a 1 L three-necked flask and 400 mL of sodium carbonate solution (10 mL) was added. The mixture was heated to reflux for 2 hours. After the reaction was completed, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was adjusted to pH 7~8 with hydrochloric acid, at which time a large amount of solid precipitated. The solution was further cooled to below 10°C, filtered and the solids were collected. The filter cake was dried under vacuum at 40 °C for 4 h to give 8.98 g of off-white solid powder in 93.6% yield. The structure of the final product 2-methyl-5,7-dihydroxychromone was confirmed by 1H-NMR and mass spectrometry. | | References | [1] Wang Y, et al. Aspergchromones A and B, two new polyketides from the marine sponge-associated fungus Aspergillus sp. SCSIO XWS03F03. J Asian Nat Prod Res. 2017 Jul;19(7):684-690. DOI:10.1080/14786419.2014.951931 |
| | 2-Methyl-5,7-dihydroxychromone Preparation Products And Raw materials |
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