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| | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Basic information |
| Product Name: | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester | | Synonyms: | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester;Demethoxyvindoline;Vindolidin;Vindolidine;Vindorosin;Vindorosine;4-acetoxy-3-hydroxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester;Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-1-methyl-, methyl ester, (2β,3β,4β,5α,12R,19α)- | | CAS: | 5231-60-7 | | MF: | C24H30N2O5 | | MW: | 426.51 | | EINECS: | | | Product Categories: | Alkaloids | | Mol File: | 5231-60-7.mol |  |
| | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Chemical Properties |
| Melting point | 167° | | alpha | D16 -31° (chloroform) | | Boiling point | 532.8±50.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | pka | 11.49±0.60(Predicted) |
| | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Usage And Synthesis |
| Description | An imidazolidinocarbazole alkaloid present in Vinca rosea L., the base is best crystallized from a mixture of C6H6 and light petroleum. It yields colourless
needles and has [α]16D - 31 ° (CHCl3). The ultraviolet spectrum consists of two absorption maxima occurring at 250 and 302 mμ. | | Uses | Vindorosine is an alkaloid from Catharanthus trichophyllus Roots. Vindorosine relaxes renal arteries[1][2]. | | References | Moza, Trojanek., Chern. & Ind., 1425 (1962)
Moza, Trojanek., Collect. Czech. Chern. Cornrnun., 28, 1419, 1427 (1963)
Synthesis:
Buchi, Matsumoto, Nishimura.']. A mer. Chern. Soc., 93, 3299 (1971) |
| | (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylic acid methyl ester Preparation Products And Raw materials |
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