4-Cholesten-3-one

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CAS:601-57-0
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Products Intro: Product Name:cholest-4-en-3-one
CAS:601-57-0
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4-Cholesten-3-one manufacturers

  • 4-Cholesten-3-one
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  • $0.00 / 1G
  • 2025-08-01
  • CAS:601-57-0
  • Min. Order: 1G
  • Purity: 99%
  • Supply Ability: 2000tons
  • Cholestenone
  • Cholestenone pictures
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  • 2025-07-31
  • CAS:601-57-0
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  • Purity: 98.41%
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  • 4-Cholesten-3-one
  • 4-Cholesten-3-one pictures
  • $0.00 / 25KG
  • 2025-07-07
  • CAS:601-57-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
4-Cholesten-3-one Basic information
Product Name:4-Cholesten-3-one
Synonyms:17-(1,5-dimethylhexyl)-10,13-dimethyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecah;17-(1,5-DIMETHYLHEXYL)-10,13-DIMETHYL-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE;4-CHOLESTEN-3-ONE;3-KETO-4-CHOLESTENE;3-OXO-4-CHOLESTENE;CHOLEST-4-ENE-3-ONE;CHOLESTENONE;3-Oxocholest-4-ene
CAS:601-57-0
MF:C27H44O
MW:384.64
EINECS:210-005-1
Product Categories:Steroids;Steroids (Others);Biochemistry
Mol File:601-57-0.mol
4-Cholesten-3-one Structure
4-Cholesten-3-one Chemical Properties
Melting point 79-82 °C
alpha 92.5 º (c=2, CHCl3)
Boiling point 451.27°C (rough estimate)
density 0.9717 (rough estimate)
refractive index 1.5100 (estimate)
storage temp. -20°C
solubility Chloroform (Sparingly), Methanol (Slightly, Heated)
form Solid
color White to Off-White
Optical Rotation[α]23/D +91.0°, c = 2 in chloroform
Water Solubility <0.5 g/L
BRN 4707774
Stability:Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference601-57-0(CAS DataBase Reference)
NIST Chemistry ReferenceCholest-4-en-3-one(601-57-0)
EPA Substance Registry SystemCholest-4-en-3-one (601-57-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS FZ7700000
TSCA Yes
HS Code 29142900
4-Cholesten-3-one Usage And Synthesis
DescriptionCholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.
Chemical Propertieswhite to light yellow crystals or powder
Uses4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.
DefinitionChEBI: Cholest-4-en-3-one is a cholestanoid that is cholest-4-ene substituted by an oxo group at position 3. It has a role as a human metabolite and a plant metabolite. It is a cholestanoid and a 3-oxo-Delta(4) steroid.
General DescriptionCholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.
4-Cholesten-3-one Preparation Products And Raw materials
Preparation Products5ALPHA-CHOLESTAN-3-ONE-->DELTA-4,6-CHOLESTADIENOL (30 MG)
Tag:4-Cholesten-3-one(601-57-0) Related Product Information
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