|
|
| | 2-Amino-5-methoxybenzamide Basic information |
| Product Name: | 2-Amino-5-methoxybenzamide | | Synonyms: | 2-Amino-5-methoxybenzamide;2-Amino-5-(methyloxy)benzamide;5-Methoxy-2-aminobenzamide;Benzamide, 2-amino-5-methoxy- | | CAS: | 1882-71-9 | | MF: | C8H10N2O2 | | MW: | 166.18 | | EINECS: | | | Product Categories: | | | Mol File: | 1882-71-9.mol |  |
| | 2-Amino-5-methoxybenzamide Chemical Properties |
| Melting point | 157-158 °C | | Boiling point | 294.4±25.0 °C(Predicted) | | density | 1.236±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | form | solid | | pka | 15.58±0.50(Predicted) | | Appearance | Off-white to light brown Solid | | InChI | 1S/C8H10N2O2/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H2,10,11) | | InChIKey | NWZIAOBMRQYTTD-UHFFFAOYSA-N | | SMILES | O=C(N)C1=CC(OC)=CC=C1N |
| Risk Statements | 43 | | Safety Statements | 36/37 | | WGK Germany | WGK 3 | | HS Code | 2924297099 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Skin Sens. 1 |
| | 2-Amino-5-methoxybenzamide Usage And Synthesis |
| Synthesis | Step 2: 5-methoxy-2-nitrobenzamide (9.70 g, 49.4 mmol) was dissolved in methanol (250 mL) and 10% palladium carbon catalyst (2.00 g) was added. The reaction mixture was stirred at room temperature and 1 atmosphere of hydrogen at 1 atmosphere for 6 hours. Upon completion of the reaction, the insoluble material was removed by filtration and the filtrate was concentrated to give 2-amino-5-methoxybenzamide (8.20 g, 99% yield) as a light yellow powder. | | References | [1] Patent: EP1953148, 2008, A1. Location in patent: Page/Page column 128-129
[2] Patent: US2015/329556, 2015, A1. Location in patent: Paragraph 1526
[3] Patent: WO2008/54599, 2008, A2. Location in patent: Page/Page column 173
[4] Patent: WO2010/104851, 2010, A1. Location in patent: Page/Page column 168
[5] Patent: WO2006/105081, 2006, A2. Location in patent: Page/Page column 157 |
| | 2-Amino-5-methoxybenzamide Preparation Products And Raw materials |
|