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| | 4-Hydroxyresveratrol Basic information |
| Product Name: | 4-Hydroxyresveratrol | | Synonyms: | 4-Hydroxyresveratrol;5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,2,3-triol;5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,2,3-triol;1,2,3-Benzenetriol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-;(E)-5-(4-Hydroxystyryl)benzene-1,2,3-triol | | CAS: | 331443-00-6 | | MF: | C14H12O4 | | MW: | 244.24 | | EINECS: | 1312995-182-4 | | Product Categories: | | | Mol File: | 331443-00-6.mol |  |
| | 4-Hydroxyresveratrol Chemical Properties |
| Boiling point | 507.8±50.0 °C(Predicted) | | density | 1.468±0.06 g/cm3(Predicted) | | pka | 9.06±0.15(Predicted) | | LogP | 2.872 (est) |
| | 4-Hydroxyresveratrol Usage And Synthesis |
| Chemical Properties | White crystalline powder | | Uses | 4-Hydroxyresveratrol (3,4,5,4'-Tetrahydroxystibene), a Resveratrol (HY-16561) analog, differentially induces pro-apoptotic p53/Bax gene expression. 4-Hydroxyresveratrol induces apoptosis in SV40 virally transformed WI38 cells (WI38VA) cells, but not in WI38 cells. 4-Hydroxyresveratrol significantly induces the expression of p53, GADD45 and Bax genes and concomitantly suppresses the expression of bcl-2 gene in WI38VA[1]. | | IC 50 | Bax | | References | [1] J Lu, et al. Resveratrol analog, 3,4,5,4'-tetrahydroxystilbene, differentially induces pro-apoptotic p53/Bax gene expression and inhibits the growth of transformed cells but not their normal counterparts. Carcinogenesis. 2001 Feb;22(2):321-8. DOI:10.1093/carcin/22.2.321 |
| | 4-Hydroxyresveratrol Preparation Products And Raw materials |
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