(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate

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(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate Basic information
Product Name:(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate
Synonyms:(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate;1-(tert-butyl) 2-methyl (2S,4S)-4-hydroxypiperidine-1,2-dicarboxylate;1,2-Piperidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4S)-;Methyl (2S,4S)-N-Boc-4-hydroxypiperidine-2-carboxylate;(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine;AN-12-H5 intermediate-1;CID 56924129;1-tert-butyl 2-methyl (2S,4S)-4-hydroxypiperidine-1,2-dicarboxylate - [B85954]
CAS:254882-14-9
MF:C12H21NO5
MW:259.3
EINECS:
Product Categories:
Mol File:254882-14-9.mol
(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate Structure
(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate Chemical Properties
Boiling point 352.1±42.0 °C(Predicted)
density 1.182
form Liquid
pka14.39±0.40(Predicted)
color Colorless to light yellow
Safety Information
HazardClass IRRITANT
MSDS Information
(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate Usage And Synthesis
UsesAN-12-H5 intermediate-1 ((2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate) is an intermediate of the viral inhibitor AN-12-H5 (HY-120900) and can be used to synthesize Antibody-Drug Conjugates (ADCs).
References[1] AN-12-H5 shows no inhibitory effect on PI4KB activity and only moderate inhibitory effects on PI 3-kinase activity[1]. DOI:10.1128/JVI.02249-10
(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate Preparation Products And Raw materials
Tag:(2S,4S)-1-tert-butyl 2-methyl-4-hydroxypiperidine-1,2-dicarboxylate(254882-14-9) Related Product Information
cis-4-Hydroxy-piperidine-1,2-dicarboxylic acid1-tert-butyl ester 2-methyl ester (2R,4R)-N-Boc-4-Hydroxypiperidine-2-carboxylic acid methyl ester (2R,4S)-N-Boc-4-hydroxypiperidine-2-carboxylic acid methyl ester Methyl N-Boc-4-hydroxypiperidine-2-carboxylate Methyl 4-Hydroxypiperidine-2-carboxylate Hydrochloride (2R,4S)-Boc-4-hydroxypiperidine-2-carboxylic acid