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| | Hydroxy Darunavir Basic information |
| Product Name: | Hydroxy Darunavir | | Synonyms: | Hydroxy Darunavir;[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-hydroxy-2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;N-[3-[[(4-aMinophenyl)sulfonyl](2-hydroxy-2-Methylpropyl)aMino]-2-hydroxy-1-(phenylMethyl)propyl]carbaMic Acid Hexahydrofuro[2,3-b]furan-3-yl Ester;Carbamic acid, N-[3-[[(4-aminophenyl)sulfonyl](2-hydroxy-2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-, hexahydrofuro[2,3-b]furan-3-yl ester | | CAS: | 1130635-75-4 | | MF: | C27H37N3O8S | | MW: | 563.67 | | EINECS: | | | Product Categories: | Amines, Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals | | Mol File: | 1130635-75-4.mol |  |
| | Hydroxy Darunavir Chemical Properties |
| density | 1.390±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | solubility | DMSO: soluble
Methanol: soluble | | pka | 11.432±0.46(predicted) |
| | Hydroxy Darunavir Usage And Synthesis |
| Uses | A metabolite of Daranavir (D193500). It is a COVID19-related research product. | | References | [1] MARC VERMEIR. Absorption, metabolism, and excretion of darunavir, a new protease inhibitor, administered alone and with low-dose ritonavir in healthy subjects.[J]. Drug Metabolism and Disposition, 2009, 37 1: 809-820. DOI: 10.1124/dmd.108.024109 |
| | Hydroxy Darunavir Preparation Products And Raw materials |
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