β-Hydroxy Thyroxine

β-Hydroxy Thyroxine Suppliers list
Company Name: sgtlifesciences pvt ltd
Tel: +8617013299288
Email: dj@sgtlifesciences.com
Products Intro: Product Name:Levothyroxine beta-Hydroxy Impurity
CAS:107849-54-7
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139
Email: orders@jknbiochem.com
Products Intro: Product Name:Levothyroxine Impurity 17
CAS:107849-54-7
Purity:0.98 Package:10G:100G
Company Name: QUALITY CONTROL SOLUTIONS LTD.
Tel: +86-0755-66853366 +86-13670046396
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Products Intro: Product Name:Thyroxine Impurity 1
CAS:107849-54-7
Purity:0.95 Package:10mg; 25mg;50mg;100mg Remarks:Brand: QCS; Can provide COA, hydrogen spectrum, mass spectrometry, liquid phase; Level: Pharmaceutical Impurity Standard
Company Name: GLP Pharma Standards  
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Products Intro: Product Name:Levothyroxine Beta Hydroxy Impurity
CAS:107849-54-7
Purity:NLT 95% Package:25 MG 50 MG 100 MG 250 MG EXTRA
Company Name: Allas Chem Technologies Pvt Ltd  
Tel: +91-9902524108
Email: krishna.alla@allaschemtech.com
Products Intro: Product Name:Levothyroxine-β-Hydroxy impurity
CAS:107849-54-7
Purity:97% Package:25 mg, 50 mg, 100 mg, 250 mg.
β-Hydroxy Thyroxine Basic information
Product Name:β-Hydroxy Thyroxine
Synonyms:Levothyroxine beta-Hydroxy Impurity;β-Hydroxy Thyroxine;β-[3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]serine;Beta-Hydroxy Thyroxine;Levothyroxine Impurity 21;Thyroxine, β-hydroxy- (7CI);Thyroxine Impurity 1;Levothyroxine Impurity 2
CAS:107849-54-7
MF:C15H11I4NO5
MW:792.87
EINECS:
Product Categories:Aromatics, Amino Acids & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals;Amino Acids & Derivatives;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:107849-54-7.mol
β-Hydroxy Thyroxine Structure
β-Hydroxy Thyroxine Chemical Properties
Melting point >175°C (dec.)
Boiling point 627.4±55.0 °C(Predicted)
density 2.706±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka1.97±0.34(Predicted)
color White to Pale Beige
InChIInChI=1/C15H11I4NO5/c16-7-3-6(4-8(17)13(7)22)25-14-9(18)1-5(2-10(14)19)12(21)11(20)15(23)24/h1-4,11-12,21-22H,20H2,(H,23,24)/t11-,12/s3
InChIKeyQIFVILYTCIFAPL-BJWPUJNWNA-N
SMILESc1(O)c(I)cc(Oc2c(I)cc(C(O)[C@@H](C(=O)O)N)cc2I)cc1I |&1:14,r|
Safety Information
MSDS Information
β-Hydroxy Thyroxine Usage And Synthesis
UsesIt has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.
UsesO-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-b-hydroxy-L-tyrosine is a Levothyroxine impurity of Thyroxine (T425600), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Thyroxine is deiodinated in peripheral tissues to the active metabolite, liothyronine, which has been used to treat hyperlipidemia.
β-Hydroxy Thyroxine Preparation Products And Raw materials
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