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| | (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Basic information |
| Product Name: | (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline | | Synonyms: | (1R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;(S)-quinuclidin-3-yl acetate;Solifenacin Impurity 42;Solifenacin impurity 10/Solifenacin R Isomer/(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;(1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline;(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline;(R)-1-Phenyl-1,2,3,4-tetrhydroisoquinoline;Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-, (1R)- | | CAS: | 180272-45-1 | | MF: | C15H15N | | MW: | 209.29 | | EINECS: | | | Product Categories: | | | Mol File: | 180272-45-1.mol |  |
| | (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Chemical Properties |
| Melting point | 78-79℃ | | density | 1.065 | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Dichloromethane (Sparingly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Pale Beige |
| | (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Usage And Synthesis |
| Uses | (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is the counterpart to (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline, the latter enantiomer being a key intermediate in the preparation of Solifenacin (S676700), an antimuscarinic agent. Since (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is produced as a by-product, it has been suggested that it should be recycled in order to obtain the S enantiomer on a larger scale. (R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is also used as a reagent to prepare quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives, compounds that act as muscarinic receptor antagonists. |
| | (1R)-Phenyl-1,2,3,4-tetrahydroisoquinoline Preparation Products And Raw materials |
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