(±)-JWH 073 N-(3-hydroxybutyl) metabolite

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(±)-JWH 073 N-(3-hydroxybutyl) metabolite Basic information
Product Name:(±)-JWH 073 N-(3-hydroxybutyl) metabolite
Synonyms:(±)-JWH 073 N-(3-hydroxybutyl) metabolite;[1-(3-hydroxybutyl)indol-3-yl]-naphthalen-1-ylmethanone;JWH-073 3-Hydroxybutyl;JWH-073 Impurity 5 ((±)-JWH-073 N-(3-hydroxybutyl) Metabolite);Methanone, [1-(3-hydroxybutyl)-1H-indol-3-yl]-1-naphthalenyl-;(±)-JWH 073 N-(3-hydroxybutyl) metabolite;JWH-073 N-(3-hydroxybutyl) metabolite, 0.1mg/ml in Methanol;JWH-073 N-(3-hydroxybutyl) metabolite, 1mg/ml in Methanol
CAS:1320363-48-1
MF:C23H21NO2
MW:343.42
EINECS:
Product Categories:
Mol File:1320363-48-1.mol
(±)-JWH 073 N-(3-hydroxybutyl) metabolite Structure
(±)-JWH 073 N-(3-hydroxybutyl) metabolite Chemical Properties
Boiling point 578.0±30.0 °C(Predicted)
density 1.17±0.1 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.5 mg/ml
form A crystalline solid
pka15.08±0.20(Predicted)
Safety Information
MSDS Information
(±)-JWH 073 N-(3-hydroxybutyl) metabolite Usage And Synthesis
DescriptionJWH 073 is a potent cannabimimetic that has been identified as an adulterant in smoking mixtures. JWH 073 N-(3-hydroxybutyl) metabolite is expected to be produced during the metabolism of JWH 073 by human liver microsomes in vitro, generated by the oxidation of the aminoalkyl chain.1,2 The biological actions of this metabolite are unknown. This product is intended for research and forensic applications.
UsesJWH-073 3-Hydroxybutyl is a urinary metabolite of JWH-073 (B693550) which acts as a partial agonist at both the CB1 and CB2 cannabinoid receptors.
References1. Wintermeyer, A., Mller, I., Thevis, M., et al. In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
2. Zhang, Q., Ma, P., Cole, R.B., et al. Identification of in vitro metabolites of JWH-015, an aminoalkylindole agonist for the peripheral cannabinoid receptor (CB2) by HPLC-MS/MS Anal. Bioanal. Chem. 386(5),1345-1355(2006).
(±)-JWH 073 N-(3-hydroxybutyl) metabolite Preparation Products And Raw materials
Tag:(±)-JWH 073 N-(3-hydroxybutyl) metabolite(1320363-48-1) Related Product Information
(1-(4-hydroxybutyl)-1H-indol-3-yl-2',4',5',6',7'-d5)(naphthalen-1-yl)-methanone (±)-JWH 073 N-(3-hydroxybutyl) metabolite-d5 ()-JWH 018 N-(4-hydroxypentyl) metabolite (R)-()-JWH 073 N-(3-hydroxybutyl) metabolite [1-(4-hydroxybutyl)indol-3-yl]-naphthalen-1-ylmethanone