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| | Docosahexaenoyl Serotonin Basic information |
| Product Name: | Docosahexaenoyl Serotonin | | Synonyms: | Docosahexaenoyl Serotonin;Docosahexaenoyl Serotonin Exclusive;(4Z,7Z,10Z,13Z,16Z,19Z)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]docosa-4,7,10,13,16,19-hexaenamide;4,7,10,13,16,19-Docosahexaenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-, (4Z,7Z,10Z,13Z,16Z,19Z)- | | CAS: | 283601-58-1 | | MF: | C32H42N2O2 | | MW: | 486.69 | | EINECS: | | | Product Categories: | | | Mol File: | 283601-58-1.mol |  |
| | Docosahexaenoyl Serotonin Chemical Properties |
| Boiling point | 698.8±55.0 °C(Predicted) | | density | 1.049±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | ≤15mg/ml in DMSO;15mg/ml in dimethyl formamide | | form | solution in ethanol. | | pka | 10.07±0.40(Predicted) | | color | Colorless to light yellow |
| | Docosahexaenoyl Serotonin Usage And Synthesis |
| Description | Docosahexaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (Catalog No. 70665). Arachidonoyl serotonin is a dual antagonist of fatty acid amide hydrolase (FAAH) and the transient receptor potential vanilloid 1 (TRPV1) channel, reducing both acute and chronic peripheral pain. The effects of replacing the arachidonoyl portion with docosahexaenoyl have not been studied. | | Uses | Docosahexaenoyl serotonin (DHA-5-HT) is an endogenous n-3 fatty acid-serotonin conjugate. Docosahexaenoyl serotonin is an inhibitor of IL-17. Docosahexaenoyl serotonin has anti-inflammatory activity[1][2]. | | Definition | ChEBI: Docosahexaenoyl Serotonin is a fatty amide. | | references | [1]. ortar g, cascio mg, de petrocellis l, et al. new n-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain. j med chem. 2007 dec 27;50(26):6554-69.
[2]. maione s, de petrocellis l, de novellis v, et al. analgesic actions of n-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid trpv1 receptors. br j pharmacol. 2007 mar;150(6):766-81. |
| | Docosahexaenoyl Serotonin Preparation Products And Raw materials |
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