| Company Name: |
Enzo Biochem Inc |
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
| Company Name: |
BIOSWAMP CO LTD |
| Tel: |
027-85586319 0278558631 |
| Email: |
bio-swampname@qq.com |
|
| | HDAC3 Polyclonal Antibody Basic information |
| | HDAC3 Polyclonal Antibody Chemical Properties |
| | HDAC3 Polyclonal Antibody Usage And Synthesis |
| Description | Histone deacetylase 3 (HDAC3) is a zinc-dependent metalloenzyme and class I HDAC.1,2 It is ubiquitously expressed and localizes primarily to the nucleus but also to the cytoplasm and plasma membrane. HDAC3 forms a complex with nuclear receptor co-repressor (NCOR) and silencing mediator of retinoic thyroid receptors (SMRT) to deacetylate histones and induce transcriptional repression and can be recruited to sites bound by activating transcription factor 2 (ATF2) without NCOR to induce inflammatory gene expression, indicating a role in transcriptional activation.2,3 HDAC3 activity is correlated with various diseases, including cancer, metabolic disorders, autoimmune disorders, neurodegenerative and CNS disorders, and cardiovascular disease.4 Cayman’s HDAC3 Polyclonal Antibody can be used for chromatin immunoprecipitation (CHiP), immunoprecipitation (IP), and Western blot (WB) applications.WARNING This product is not for human or veterinary use. |
| | HDAC3 Polyclonal Antibody Preparation Products And Raw materials |
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