- HBX 19818
-
- $32.00 / 1mg
-
2026-03-13
- CAS:1426944-49-1
- Min. Order:
- Purity: 98.76%
- Supply Ability: 10g
|
| | HBX 19818 Basic information |
| Product Name: | HBX 19818 | | Synonyms: | HBX 19818;9-Chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-2-acridinecarboxamide;HBX19818; HBX-19818;N-[3-[benzyl(methyl)amino]propyl]-9-chloro-5,6,7,8-tetrahydroacridine-2-carboxamide;2-Acridinecarboxamide, 9-chloro-5,6,7,8-tetrahydro-N-[3-[methyl(phenylmethyl)amino]propyl]-;HBX 19818,Deubiquitinase,Inhibitor,DUBs,HBX19818,inhibit,HBX-19818;HBX 19818, 10 mM in DMSO | | CAS: | 1426944-49-1 | | MF: | C25H28ClN3O | | MW: | 421.96 | | EINECS: | | | Product Categories: | | | Mol File: | 1426944-49-1.mol |  |
| | HBX 19818 Chemical Properties |
| Boiling point | 631.2±55.0 °C(Predicted) | | density | 1.206±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO:12.5(Max Conc. mg/mL);29.62(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.47(Max Conc. mM)
Water:5.0(Max Conc. mg/mL);0.47(Max Conc. mM) | | form | Solid | | pka | 13.67±0.20(Predicted) | | color | Light yellow to yellow |
| | HBX 19818 Usage And Synthesis |
| Uses | HBX 19818 is a specific inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 28.1 μM. | | References | [1] Reverdy C, et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. Chem Biol. 2012 Apr 20;19(4):467-77. DOI:10.1016/j.chembiol.2012.02.007 |
| | HBX 19818 Preparation Products And Raw materials |
|