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| | (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Basic information |
| Product Name: | (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione | | Synonyms: | Clobetasol impurity J (PhEur);Clobetasol Related Compound A (USP);Clobetasol Propionate EP Impurity J;Clobetasol Propionate Impurity 10(Clobetasol Propionate EP Impurity J);2-tert-butyl-1'-(7-methyl-3a,7a-dihydro-1H-indazole-5-carbonyl)spiro[4,6-dihydropyrazolo[3,4-c]pyridine-5,4'-piperidine]-7-one;Clobetasol Propionate USP Related Compound A/(17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione;Clobetasol Propionate USP Related Compound A;Clobetasol Propionate EP IMP J | | CAS: | 1486466-31-2 | | MF: | C25H30ClFO4 | | MW: | 448.95 | | EINECS: | | | Product Categories: | | | Mol File: | 1486466-31-2.mol | ![(17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Structure](CAS/20180906/GIF/1486466-31-2.gif) |
| | (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Chemical Properties |
| Melting point | >276°C (dec.) | | Boiling point | 563.7±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Dioxane (Very Slightly, Heated, Sonicated), DMSO (Slightly, Heated) | | pka | 12.96±0.70(Predicted) | | color | White to off-White | | InChIKey | LXZPFTQONPQBQD-TUZVJILZSA-N |
| | (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Usage And Synthesis |
| Uses | (17R)-4’-Chloro-5’-ethyl-9-fluoro-11β-hydroxy-16β-methylspiro[androsta-1,4-diene-17,2’(3’H)-furan]-3,3’-dione, is an impurity of Clobetasol (C583490), a topical corticosteroid, and a Glucocorticoid, used as an anti-inflammatory agent. |
| | (17R)-4'-Chloro-5'-ethyl-9-fluoro-11β-hydroxy-16β-Methylspiro[androsta-1,4-diene-17,2'(3'H)-furan]-3,3'-dione Preparation Products And Raw materials |
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