| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:1-desoxymethylsphingosine (m17:1)
CAS:1246303-16-1
Purity:>99% Package:1MG;2.5MG;5MG
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| Company Name: |
Chengdu Huachun Technology Co., Ltd
|
| Tel: |
400-1166-196 15982826727 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:1-desoxymethylsphingosine (m17:1)
CAS:1246303-16-1
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| Company Name: |
SHANGHAI ZZBIO CO., LTD.
|
| Tel: |
15102117276 19921389125 |
| Email: |
tech@zzbioco.com |
| Products Intro: |
Product Name:1-desoxymethylsphingosine (m17:1)
CAS:1246303-16-1
Purity:0.99 Package:1mg
|
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| | 1-desoxyMethylsphingosine (M17:1) Basic information |
| | 1-desoxyMethylsphingosine (M17:1) Chemical Properties |
| storage temp. | -20°C | | form | powder | | InChI | 1S/C17H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19)16-18/h14-15,17,19H,2-13,16,18H2,1H3/b15-14+/t17-/m1/s1 | | InChIKey | NTZGVZKEAIALQE-IAOULYHDSA-N | | SMILES | CCCCCCCCCCCCC/C=C/[C@](O)([H])CN |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | 1-desoxyMethylsphingosine (M17:1) Usage And Synthesis |
| Uses | 1-desoxymethylsphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line. | | Biological Activity | 1-desoxymethylsphingosine is less neurotoxic compared to 1-desoxysphingosine in dorsal root ganglion neuronscultures Mutations in the palmitoyltransferase (SPT) in hereditary sensory neuropathy type 1 (HSAN-1), due to altered substrate specificity 1-desoxymethylsphinganine and 1-deoxy-sphinganine which are further converted to -deoxy(methyl)-ceramide and 1-deoxy(methyl)-sphingosine (1-deoxy(methyl)-SO). However, they lack the hydroxyl group essential for glycosphingolipid generation, resulting in accumulation of intermediate products. |
| | 1-desoxyMethylsphingosine (M17:1) Preparation Products And Raw materials |
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