| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
marketing1@energy-chemical.com |
|
| | 4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide Basic information |
| | 4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide Chemical Properties |
| Boiling point | 500.5±50.0 °C(Predicted) | | density | 1.412±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: ≥15mg/mL | | pka | 8.79±0.50(Predicted) | | form | powder | | color | white to tan |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | 3 |
| | 4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide Usage And Synthesis |
| Uses | 2002-H20 is an inhibitor of Aβ42-induced cytotoxicity, with the activity of reducing the cytotoxicity of Alzheimer's disease Aβ peptide by binding to it. 2002-H20 protects cells and reduces Aβ toxicity by promoting fibril formation, possibly by accelerating Aβ aggregation. The screening method of 2002-H20 effectively identifies compounds that reduce Aβ toxicity and presents potential inhibitory leads[1]. | | Definition | ChEBI: 4-amino-N-[3-(3H-1,3-benzoxazol-2-ylidene)-4-oxo-1-cyclohexa-1,5-dienyl]benzamide is a member of benzamides. | | References | [1] Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity |
| | 4-amino-N-[3-(2-benzoxazolyl)-4-hydroxyphenyl]-benzamide Preparation Products And Raw materials |
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