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| | Heat shock protein HSP 90-alpha Basic information |
| Product Name: | Heat shock protein HSP 90-alpha | | Synonyms: | Anti-HSP90A, C-Terminal antibody produced in rabbit;Monoclonal Anti-HSP90AA1 antibody produced in mouse;MONOCLONAL ANTI-HSP90 antibody produced in mouse;Heat shock protein HSP 90-alpha;HSP90A;HSP90AA1;HSPCA;HSPCAL3 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | ELISA Kit-FOR ELISA Kit | | Mol File: | Mol File | ![Heat shock protein HSP 90-alpha Structure]() |
| | Heat shock protein HSP 90-alpha Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | biological source | human | | Water Solubility | water: soluble | | Cosmetics Ingredients Functions | SKIN CONDITIONING |
| Hazard Codes | Xi,T,Xn | | Risk Statements | 36/37/38-61-22 | | Safety Statements | 26-45-53 | | WGK Germany | WGK 1 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Eye Irrit. 2
Repr. 1B
Skin Irrit. 2 |
| | Heat shock protein HSP 90-alpha Usage And Synthesis |
| Uses | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. | | Biological Activity | HSP90α (he at shock protein 90α) is involved intracellularly in the folding, assembly-disassembly and activation of multiple types of target proteins such as kinases, steroid hormone receptors and transcription factors. Extracellularly this protein is also required for neuronal and dermal fibroblast motility, and melanoma migration, invasion and metastasis. Extracellular HSP90α induces pro-invasive protein matrix metalloproteinase-2 (MMP-2), thereby promoting tumor invasiveness. This protein facilitates the migration of dermal and epidermal cells to the site of wound in a surface receptor LRP-1 (LDL receptor-related protein 1)-dependent manner, and is thus, involved in wound healing. In an early stage of the antigen processing pathway, HSP90α might function as a chaperone for precursors of pMHC I (peptide-loaded major histocompatibility I complexes). |
| | Heat shock protein HSP 90-alpha Preparation Products And Raw materials |
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