| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
|
| Product Name: | PAR-1 | | Synonyms: | Anti-MARK2, N-Terminal antibody produced in rabbit;Monoclonal Anti-PAR1 antibody produced in mouse;ELKL motif kinase 1;MAP/microtubule affinity-regulating kinase 2;PAR-1;D15S227E;MARK2, active, GST tagged human;MGC99619 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![PAR-1 Structure]() |
| | PAR-1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous glycerol solution | | biological source | mouse | | Specific Activity | 676-914nmol/min·mg |
| WGK Germany | 1 | | Storage Class | 10 - Combustible liquids |
| | PAR-1 Usage And Synthesis |
| Uses | MARK2 or microtubule affinity-regulating kinase 2 is a member of the Par-1 family of serine/threonine protein kinases. MARK2 is an important regulator of cell polarity in epithelial and neuronal cells and controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. MARK2 is a key target of H. pylori CagA in the disorganization of gastric epithelial architecture underlying mucosal damage, inflammation, and carcinogenesis. MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation. MARK2 function in the establishment of T cell polarity following engagement to an APC. |
| | PAR-1 Preparation Products And Raw materials |
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