| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Recombinant Human Neuritin/NRN1 Protein, His Tag
Purity:90% as determined by SDS-PAGE Package:50ug;100ug
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Neuritin human
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| Company Name: |
shlmai
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| Tel: |
021-67680335 13052188602 |
| Email: |
sale1@shlmai.net |
| Products Intro: |
Product Name:NRN1
Purity:99% Package:>=48T/RMB 1520;>=96T/RMB 1960
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| Company Name: |
Biorbyt Ltd.
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| Tel: |
+44 (0)1223 859 353 |
| Email: |
info@biorbyt.com |
| Products Intro: |
Product Name:Recombinant Human Neuritin/NRN1 Protein, His Tag
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| Product Name: | NRN1 | | Synonyms: | NRN1;Neuritin human;CPG15;Recombinant Human Neuritin/NRN1 Protein, His Tag | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![NRN1 Structure]() |
| storage temp. | -20°C | | form | lyophilized | | color | white to off-white | | biological source | human |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| Uses | NRN1 (neuritin 1) is a highly conserved extracellular GPI (glycosylphosphatidylinositol)-anchored protein that was initially identified in rat hippocampal dentate gyrus in a screening of candidate kainic acid-induced plasticity related genes. This protein is also secreted in a soluble form.
Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.8kDa polypeptide monomers, each containing 89 amino acid residues. | | Biological Activity | NRN1 (neuritin 1) is implicated in synaptic plasticity during brain development, and is an activity-dependent protein. Synaptic plasticity is dependent upon neuronal migration, and a study shows th at NRN1 protein facilitates neuronal cell migration, and its levels influence microtubule stability. This protein also promotes dendritic arborization and synapse maturation in the central nervous system (CNS). It facilitates the survival of neural progenitors and differentiated neurons during early embryonic development, and during late development it is responsible for the maturation and formation of synapses by promoting the growth and stabilization of axons and dendrites. Study in human microendothelial cells (HMEC-1) shows th at the expression of this protein is hypoxia-induced, and it is a hypoxic perinecrotic marker.
Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.8kDa polypeptide monomers, each containing 89 amino acid residues. |
| | NRN1 Preparation Products And Raw materials |
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