Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid)

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Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid) Basic information
Product Name:Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid)
Synonyms:L-Valinamide, N-acetyl-L-leucyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-;Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid)
CAS:402832-01-3
MF:C22H36N4O9
MW:500.54
EINECS:
Product Categories:
Mol File:Mol File
Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid) Structure
Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid) Chemical Properties
Boiling point 914.6±65.0 °C(Predicted)
density 1.238±0.06 g/cm3(Predicted)
storage temp. Store at 0°C
solubility water: 1 mg/mL
pka4.19±0.10(Predicted)
form lyophilized solid
color white
Water Solubility water: 1mg/mL
SequenceAc-Leu-Glu-Val-Asp-CHO
InChIKeyMXGJLIBJKIIQSF-FPXQBCRKSA-N
SMILESN([C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)CCC(=O)O
Safety Information
WGK Germany WGK 1
Storage Class11 - Combustible Solids
MSDS Information
Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid) Usage And Synthesis
UsesAc-LEVD-CHO is a caspase-4 inhibitor. Ac-LEVD-CHO is a peptide with the sequence of Ac-Leu-Glu-Val-Asp-al[1].
Biological ActivityCell permeable: no', 'Primary Target
caspase-4', 'Product does not compete with ATP.', 'Reversible: yes
IC 50Caspase-4
References[1] Hye-Kyoung Jun, et al. Treponema denticola, Porphyromonas gingivalis, and Tannerella forsythia induce cell death and release of endogenous danger signals. Arch Oral Biol. 2017, 72, 73. DOI:10.1016/j.archoralbio.2016.09.010
Ac-Leu-Glu-Val-Asp-aldehyde (pseudo acid) Preparation Products And Raw materials
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